NBC Debuts ‘St. Denis Medical’ Season Three First Look

Reel Perspectives

September 23, 2026

The chaos inside Oregon’s most underfunded hospital is about to reach a whole new level.

NBC has unveiled exciting first-look photos from the upcoming third season of “St. Denis Medical,” giving fans an early glimpse at the beloved Emergency Department staff as they navigate another round of professional disasters, personal struggles and complicated romantic entanglements.

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Set inside an understaffed and underfunded Oregon hospital, “St. Denis Medical” follows the dedicated medical professionals who show up every day determined to care for their patients—even when the hospital is running on fumes and their own lives are barely holding together. Those personal complications become even harder to ignore as relationships shift, romantic sparks fly and tensions push some St. Denis employees closer to the breaking point.

The new season promises plenty of the sharp workplace comedy, heartfelt character moments and wonderfully awkward situations that have made the series a standout. Behind the hospital doors, friendships will be tested, relationships will become increasingly complicated and the staff will once again attempt to keep St. Denis functioning despite seemingly endless obstacles.

Returning for Season 3 are Wendi McLendon-Covey, David Alan Grier, Allison Tolman, Josh Lawson, Kahyun Kim, Mekki Leeper and Kaliko Kauahi, bringing the series' eccentric and lovable medical team back together for another unpredictable chapter.

Eric Ledgin serves as showrunner and executive producer. Justin Spitzer, Simon Heuer, Bridget Kyle and Vicky Luu also executive produce. “St. Denis Medical” is produced by Universal Television, a division of Universal Studio Group, More Bees, Inc. and Spitzer Holding Company.

St. Denis Medical Season 3 Premieres Monday, November 2 on NBC

Streaming Next Day on Peacock